t-butyl chloroformate - Names and Identifiers
t-butyl chloroformate - Physico-chemical Properties
Molecular Formula | C5H9ClO2
|
Molar Mass | 136.57676 |
t-butyl chloroformate - Introduction
t-butyl chloroformate(t-butyl chloroformate) is an organic compound with the chemical formula (CH3)3CCOCl. It is a colorless liquid with a pungent odor at room temperature. The following is a description of the nature, use, preparation and safety information of t-butyl chloroformate:
Nature:
-The molecular weight is 122.55g/mol.
-Liquid at room temperature, boiling point 72-74 ℃, density 0.973 g/mL.
-Soluble in organic solvents such as ethers, alcohols and ketones, react with water to release toxic gases.
Use:
- t-butyl chloroformate can be used as reagents in organic synthesis. It is commonly used to protect hydroxyl (OH) and amine (NH) groups.
-In synthetic chemistry, it is often used as an acylation reagent in esterification, hydroxyacylation, amination and other reactions.
Preparation Method:
-The more common method of preparing t-butyl chloroformate is to react tert-butyl chloromethanol and phosphorus trichloride (PCl3) to form.
Safety Information:
- t-butyl chloroformate are highly volatile and irritating, and contact with skin and eyes should be avoided.
-During operation, wear appropriate protective gloves and glasses to ensure a well-ventilated laboratory environment.
-When storing, keep it in a sealed container and avoid direct sunlight and high temperature environment.
Please note that the above information is for reference only. If you need to use t-butyl chloroformate, please be sure to consult relevant safety materials and chemical manuals first, and operate under suitable experimental conditions.
Last Update:2024-04-10 22:29:15